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POMIFERIN

CAS No.:
572-03-2
Catalog Number:
AG00EGMR
Molecular Formula:
C25H24O6
Molecular Weight:
420.4545
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Product Description
Catalog Number:
AG00EGMR
Chemical Name:
POMIFERIN
CAS Number:
572-03-2
Molecular Formula:
C25H24O6
Molecular Weight:
420.4545
IUPAC Name:
3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
InChI:
InChI=1S/C25H24O6/c1-13(2)5-7-15-21(28)20-22(29)17(14-6-8-18(26)19(27)11-14)12-30-24(20)16-9-10-25(3,4)31-23(15)16/h5-6,8-12,26-28H,7H2,1-4H3
InChI Key:
GHCZYXUOYFOXIP-UHFFFAOYSA-N
SMILES:
CC(=CCc1c2OC(C)(C)C=Cc2c2c(c1O)c(=O)c(co2)c1ccc(c(c1)O)O)C
UNII:
74YIS40APM
NSC Number:
5113
Properties
Complexity:
792  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
420.157g/mol
Formal Charge:
0
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
420.461g/mol
Monoisotopic Mass:
420.157g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
96.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.5  
Literature
Title Journal
Regulation of immune responses by histone deacetylase inhibitors. ISRN hematology 20120101
Antiproliferative activity of pomiferin in normal (MCF-10A) and transformed (MCF-7) breast epithelial cells. Journal of agricultural and food chemistry 20111228
Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin. PloS one 20110101
Oxidative stress in dog with heart failure: the role of dietary Fatty acids and antioxidants. Veterinary medicine international 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats. Interdisciplinary toxicology 20100601
Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells. Experimental cell research 20100310
Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. Bioorganic & medicinal chemistry 20100115
Examining the genomic influence of skin antioxidants in vitro. Mediators of inflammation 20100101
Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801
Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide. Journal of pharmaceutical and biomedical analysis 20080910
Outlook on Thailand's genomics and computational biology research and development. PLoS computational biology 20080701
Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera. Bioorganic & medicinal chemistry letters 20070901
[Examination of the antioxidative and antidiabetic effect of pomiferin in alloxan-induced diabetes mellitus in an experiment (a pilot study)]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20070601
[Protective effects of the flavonoids osajin and pomiferin on heart ischemia-reperfusion]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20060701
Effects of prenylated isoflavones osajin and pomiferin in premedication on heart ischemia-reperfusion. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20060701
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Proteomic profiling of cholangiocarcinoma cell line treated with pomiferin from Derris malaccensis. Proteomics 20051101
Antioxidative and EROD activities of osajin and pomiferin. Fitoterapia 20040301
Antioxidant isoflavones in Osage orange, Maclura pomifera (Raf.) Schneid. Journal of agricultural and food chemistry 20031022
Pomiferin. Acta crystallographica. Section C, Crystal structure communications 20030301
Properties