Home Other Building Blocks Niceritrol

Niceritrol

CAS No.:
5868-05-3
Catalog Number:
AG00EFVR
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
>98.0%(HPLC)
1 week
United States
$277
- +
Product Description
Catalog Number:
AG00EFVR
Chemical Name:
Niceritrol
CAS Number:
5868-05-3
MDL Number:
MFCD00215982
IUPAC Name:
[3-(pyridine-3-carbonyloxy)-2,2-bis(pyridine-3-carbonyloxymethyl)propyl] pyridine-3-carboxylate
InChI:
InChI=1S/C29H24N4O8/c34-25(21-5-1-9-30-13-21)38-17-29(18-39-26(35)22-6-2-10-31-14-22,19-40-27(36)23-7-3-11-32-15-23)20-41-28(37)24-8-4-12-33-16-24/h1-16H,17-20H2
InChI Key:
KUEUWHJGRZKESU-UHFFFAOYSA-N
EC Number:
227-519-7
UNII:
F54EHJ34MV
Properties
Complexity:
745  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
556.159g/mol
Formal Charge:
0
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
556.531g/mol
Monoisotopic Mass:
556.159g/mol
Rotatable Bond Count:
16  
Topological Polar Surface Area:
157A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.3  
Literature
Title Journal
Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells. Journal of inflammation research 20120101
Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol. Clinical and experimental nephrology 20101201
Binder blinders-niacin of omission? American journal of kidney diseases : the official journal of the National Kidney Foundation 20100401
The mechanism and mitigation of niacin-induced flushing. International journal of clinical practice 20090901
Transplantation of bone marrow-derived mesenchymal stem cells improves diabetic polyneuropathy in rats. Diabetes 20081101
Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism. Endocrine journal 20061201
[Dyslipidemia in renal failure]. Nihon rinsho. Japanese journal of clinical medicine 20040601
Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial. The American journal of medicine 20030401
Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030101
The effects of combination therapy with niceritrol and pravastatin on hyperlipidaemia. The Journal of international medical research 20020101
Effect of niceritrol on streptozocin-induced diabetic neuropathy in rats. Diabetes 19920501
Enzymatic hydrolysis of pentaerythritoltetranicotinate and meso-inositolhexanicotinate in blood and tissues. Arzneimittel-Forschung 19790101
Properties