Home Other Building Blocks Solutol HS 15

Solutol HS 15

CAS No.:
61909-81-7
Catalog Number:
AG00EFMK
Molecular Formula:
C20H40NO4
Molecular Weight:
358.5359
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50g
1 week
United States
$154
- +
Product Description
Catalog Number:
AG00EFMK
Chemical Name:
Solutol HS 15
CAS Number:
61909-81-7
Molecular Formula:
C20H40NO4
Molecular Weight:
358.5359
IUPAC Name:
2-hydroxyethyl 12-hydroxyoctadecanoate
InChI:
InChI=1S/C20H40O4/c1-2-3-4-11-14-19(22)15-12-9-7-5-6-8-10-13-16-20(23)24-18-17-21/h19,21-22H,2-18H2,1H3
InChI Key:
JVKUCNQGESRUCL-UHFFFAOYSA-N
SMILES:
CCCCCCC(CCCCCCCCCCC(=O)OCCO)O.[N]
NSC Number:
7395
Properties
Complexity:
268  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
344.293g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
344.536g/mol
Monoisotopic Mass:
344.293g/mol
Rotatable Bond Count:
19  
Topological Polar Surface Area:
66.8A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
5.9  
Literature
Title Journal
A propofol microemulsion with low free propofol in the aqueous phase: formulation, physicochemical characterization, stability and pharmacokinetics. International journal of pharmaceutics 20121015
Pharmaceutical excipients influence the function of human uptake transporting proteins. Molecular pharmaceutics 20120904
CriticalSorb: a novel efficient nasal delivery system for human growth hormone based on Solutol HS15. Journal of controlled release : official journal of the Controlled Release Society 20120820
In-situ phase transition from microemulsion to liquid crystal with the potential of prolonged parenteral drug delivery. International journal of pharmaceutics 20120715
Physicochemical characterization and an injection formulation study of water insoluble ZCVI₄-2, a novel NO-donor anticancer compound. Archives of pharmacal research 20120701
In situ controlled crystallization as a tool to improve the dissolution of Glibenclamide. International journal of pharmaceutics 20120530
Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier. International journal of pharmaceutics 20120315
Ferrociphenol lipid nanocapsule delivery by mesenchymal stromal cells in brain tumor therapy. International journal of pharmaceutics 20120214
Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. International journal of pharmaceutics 20120214
In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model. International journal of pharmaceutics 20120214
Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance. International journal of pharmaceutics 20120117
A comparative study of non-lipid nanoemulsion of propofol with solutol and propofol emulsion with lecithin. Revista brasileira de anestesiologia 20120101
Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110901
Self-microemulsifying drug delivery system for improved oral bioavailability of dipyridamole: preparation and evaluation. Archives of pharmacal research 20110701
Case studies with new excipients: development, implementation and regulatory approval. Therapeutic delivery 20110701
Inner ear biocompatibility of lipid nanocapsules after round window membrane application. International journal of pharmaceutics 20110214
[Effect of three penetration enhancers on corneal permeability of mangiferin in vitro]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
Formulation and evaluation of an alternative triglyceride-free propofol microemulsion. Archives of pharmacal research 20100901
The effect of novel surfactants and Solutol HS 15 on paclitaxel aqueous solubility and permeability across a Caco-2 monolayer. Journal of pharmaceutical sciences 20100801
Antinociceptive activity of Delta9-tetrahydrocannabinol non-ionic microemulsions. International journal of pharmaceutics 20100630
[Studies on preparation and dissolution test in vitro of sustained-release dropping pills of curcumin]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101
Emulsifiers' composition modulates venous irritation of the nanoemulsions as a lipophilic and venous irritant drug delivery system. AAPS PharmSciTech 20090901
The encapsulation of DNA molecules within biomimetic lipid nanocapsules. Biomaterials 20090601
Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results. International journal of pharmaceutics 20090105
In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug. Drug delivery 20080901
Nano-emulsions and nanocapsules by the PIT method: an investigation on the role of the temperature cycling on the emulsion phase inversion. International journal of pharmaceutics 20071101
Preparation and characterization of a self-emulsifying pellet formulation. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070501
Formulation of sustained release nanoparticles loaded with a tripentone, a new anticancer agent. International journal of pharmaceutics 20060831
Mechanistic study of solubility enhancement of nifedipine using vitamin E TPGS or solutol HS-15. Drug delivery 20060101
Convection-compensating diffusion experiments with phase-sensitive double-quantum filtering. Journal of magnetic resonance (San Diego, Calif. : 1997) 20050601
In vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam. Biopharmaceutics & drug disposition 20040101
Impact of Solutol HS 15 on the pharmacokinetic behavior of midazolam upon intravenous administration to male Wistar rats. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030701
The influence of lipid nanocapsule composition on their size distribution. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030101
Improved oral bioavailability of cyclosporin A in male Wistar rats. Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension. International journal of pharmaceutics 20021001
Solutol and cremophor products as new additives in suppository formulation. Drug development and industrial pharmacy 20020101
Properties