sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Imidaprilat

Imidaprilat

CAS No.:
89371-44-8
Catalog Number:
AG003XKL
Molecular Formula:
C18H23N3O6
Molecular Weight:
377.3917
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG003XKL
Chemical Name:
Imidaprilat
CAS Number:
89371-44-8
Molecular Formula:
C18H23N3O6
Molecular Weight:
377.3917
MDL Number:
MFCD00870778
IUPAC Name:
(4S)-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
InChI:
InChI=1S/C18H23N3O6/c1-11(15(22)21-14(17(25)26)10-20(2)18(21)27)19-13(16(23)24)9-8-12-6-4-3-5-7-12/h3-7,11,13-14,19H,8-10H2,1-2H3,(H,23,24)(H,25,26)/t11-,13-,14-/m0/s1
InChI Key:
VFAVNRVDTAPBNR-UBHSHLNASA-N
SMILES:
C[C@@H](C(=O)N1C(=O)N(C[C@H]1C(=O)O)C)N[C@H](C(=O)O)CCc1ccccc1
UNII:
WUU07Y30IA
Properties
Complexity:
590  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
377.159g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
377.397g/mol
Monoisotopic Mass:
377.159g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
127A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.4  
Literature
Title Journal
Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes. American journal of hypertension 20100501
Different inhibitory effects in rat and human carboxylesterases. Drug metabolism and disposition: the biological fate of chemicals 20090501
Angiotensin-converting enzyme inhibitor attenuates monocyte adhesion to vascular endothelium through modulation of intracellular zinc. The Journal of pharmacology and experimental therapeutics 20071201
Imidapril: a review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure. Drugs 20070101
Imidaprilat suppresses nonylphenol and 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxyl radical generation in rat striatum. Neuroscience research 20060301
Imidaprilat, an angiotensin-converting enzyme inhibitor exerts neuroprotective effect via decreasing dopamine efflux and hydroxyl radical generation induced by bisphenol A and MPP+ in rat striatum. Brain research 20060203
Protective effect of imidaprilat, an angiotensin-converting enzyme inhibitor on *OH generation in rat myocardium. Biochimica et biophysica acta 19991018
No relation of the suppressive effect on the sympathetic nervous system to the acute hypotension caused by imidapril and enalapril. Japanese journal of pharmacology 19931101
Properties